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Patented Technologies

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Patented Technologies
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Patented Technologies

Patented Technologies
28/01/2009

Dexcel Pharma has invented 9 unique, modified-release, drug delivery technologies:

Marketed Drug Delivery Technologies

Zero Neutralized Delayed Release (ZNDR)
Reversible neutralized enteric coating. Resistance at full acid pH range without need for protective sub-coat.
  • GI therapeutic areas, such as Omepradex® and Omepradex-Z® (generic to Prilosec® and Prilosec OTC®).
  • Tablets/capsules marketed in US, UK, Israel and Australia.

Periodontal Pocket Delivery System (PerioChip®)
Local release of antiseptic agent using unique biodegradable matrix.

  • Marketed in US (NDA), 12 EU member states and Singapore, soon to be launched in Korea.


Preconcentrate Technology (PT)
Soft gelatin capsules filled with liquid containing insoluble drugs.

  • Deximune® Ciclosporine (generic to Neoral Sandimmune®).
  • Marketed in Israel, UK, Germany and Denmark, soon to be launched in other EU and CEE countries.

Coated Extended Release Technology (CERT)
Extended-release tablet-coating formulation, comprising specific mixture of polymers surrounding controlled-release core.

  • ViePax® XR Venlafaxine (generic to Effexor® XR).
  • Marketed in Israel, UK, Germany, Netherlands, Greece, Portugal and Singapore, soon to be launched in Italy.


Innovative Drug Delivery Technologies

Time-Controlled Delivery System (TCDS®)
Unique delivery technology providing time-controlled release, in tablets and capsules, independent of pH and enzymes in the GI system, for burst and extended release in single or double pulses.

  • Increased bioavailability, efficacy and safety.
  • Extended, controlled GI site absorption.
  • Independent of pH, fluid viscosity, and GI agitation rate.


Fast Dissolving Microsphere-Based Tablets

  • Unique compressible multi-unit system.
  • Designed for fast dissolving, with delayed-release profile.

Technologies Under Development
  • Second generation of PerioChip® technology.
  • Buccal Controlled-Release Liposome (tablet).
  • Site Specific Delivery System (tablets/capsules).
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